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| Agents | Nature of the agent | Disease type | Phase | Reference |
|---|---|---|---|---|
| Obatoclax | BH3 mimetic | SCLC and myelofibrosis | I | 139, 140 |
| Gossypol | BH3 mimetic | Metastic breast cancer and CRPC | I and II | 141, 142, 143 |
| ABT-263 | BH3 mimetic | Advanced haematological cancers | I | 144 |
| ABT-199 | BH3 mimetic | CLL | I | 145 |
Abbreviations: SCLC, small-cell lung cancer; CRPC, castration-resistant prostate cancer; CLL, chronic lymphocytic leukaemia
