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. 2016 Jan 14;7(1):e2047. doi: 10.1038/cddis.2015.394

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Copyright © 2016 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Givinostat induced differentiation of a TLX1-driven xenograft. (a) Flow cytometry analysis of CD1a (top) and CD4/CD8 (bottom) expression in human CD45-positive spleen cells isolated from PD-TALL8 leukemia recipient mice treated with Givinostat or vehicle (n=8/9 mice/group) for 5 days. A representative flow cytometry plot is shown. (b) Histograms report the mean values±S.D. of CD1a (top) and CD4 (bottom) in all mice analyzed. Data were analyzed with Mann–Whitney test with Bonferroni correction (**P<0.01)