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. 2016 Jan 14;7(1):e2043. doi: 10.1038/cddis.2015.408

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Copyright © 2016 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Overexpression of EMC6 inhibits the development of GBM in vivo. (a) The U87 with or without EMC6-overexpression cells stably expressing luciferase were injected into intracranial brain of BALB/c nude mice. Luciferase signal in different treatment groups was detected every 7 days by in vivo bioluminescence imaging (IVIS 100 Imaging System) to monitor the development of GBM until 4 weeks. n=6. (b) Plotting diagram shows the changes of relative luminescence in the indicated groups of mice during 3 weeks. Data are means±S.D., ***P<0.001. n=6. (c) Survival differences among the indicated groups of mice were shown by survival curve until all mice were dead. n=6. (d) The survival day differences among the indicated groups of mice were shown by survival curve until all mice were dead. n=6. ***P<0.001