Table A5.
Total cardiovascular disease-related healthcare costs
| Coefficient (£) | Standard error | Lower 95% CI (£) | Upper 95% CI (£) | |
|---|---|---|---|---|
| Background cost per 90 days | ||||
| Baseline (for a man aged 69 with stable angina and no other co-morbidities) | 224 | 7.74 | 209 | 239 |
| Baseline age (centred) | 6 | 0.32 | 6 | 7 |
| Female | −23 | 7.65 | −38 | −8 |
| Increase per 90 days | 7 | 0.15 | 6 | 7 |
| SCAD diagnosis (relative to stable angina) | ||||
| Other CHD | 2 | 9.39 | −16 | 21 |
| NSTEMI | 145 | 13.66 | 119 | 172 |
| STEMI | 29 | 15.77 | −2 | 60 |
| Unstable angina | 125 | 11.32 | 103 | 147 |
| CVD co-morbidities | ||||
| History of heart failure | 248 | 9.29 | 230 | 266 |
| History of atrial fibrillation | 221 | 10.90 | 199 | 242 |
| History of PAD | 242 | 13.53 | 216 | 269 |
| Non-CVD co-morbidities | ||||
| Diabetes | 194 | 10.43 | 173 | 214 |
| History of liver disease | 279 | 38.68 | 203 | 355 |
| History of COPD | 142 | 8.79 | 124 | 159 |
| History of cancer | 154 | 13.34 | 128 | 180 |
| History of renal disease | 418 | 16.07 | 386 | 449 |
| Incremental cost of non-fatal MI | ||||
| Cost in first 90-day period | 4854 | 29.55 | 4796 | 4911 |
| Cost in second 90-day period | 1209 | 31.64 | 1147 | 1271 |
| Cost in third 90-day period | 640 | 33.63 | 574 | 706 |
| Cost in fourth 90-day period | 675 | 35.08 | 606 | 744 |
| Cost in subsequent 90-day periods | 481 | 15.64 | 451 | 512 |
| Additional incremental cost of non-fatal MI for patients with diabetes | ||||
| Additional cost in first 90-day period | 674 | 65.05 | 546 | 801 |
| Cost in second 90-day period | 1042 | 70.02 | 904 | 1179 |
| Cost in third 90-day period | 660 | 74.71 | 514 | 807 |
| Cost in fourth 90-day period | 403 | 78.04 | 250 | 556 |
| Cost in subsequent 90-day periods | 280 | 35.33 | 210 | 349 |
| Incremental cost of non-fatal ischaemic stroke | ||||
| Cost in first 90-day period | 5957 | 30.95 | 5897 | 6018 |
| Cost in second 90-day period | 1151 | 32.69 | 1087 | 1215 |
| Cost in third 90-day period | 675 | 35.29 | 606 | 744 |
| Cost in fourth 90-day period | 539 | 37.08 | 466 | 612 |
| Cost in subsequent 90-day periods | 448 | 16.86 | 415 | 481 |
| Incremental cost of non-fatal haemorrhagic stroke | ||||
| Cost in first 90-day period | 6836 | 107.73 | 6625 | 7047 |
| Cost in second 90-day period | 1517 | 119.28 | 1284 | 1751 |
| Cost in third 90-day period | 585 | 133.45 | 324 | 847 |
| Cost in fourth 90-day period | 393 | 142.02 | 115 | 671 |
| Cost in subsequent 90-day periods | 670 | 62.69 | 547 | 792 |
| Cost of fatal events | ||||
| Fatal CVD event | 2071 | 21.30 | 2029 | 2113 |
| Fatal non-CVD event | 1737 | 17.28 | 1703 | 1771 |