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| Species | t1/2 (min) | CLint, in vitro (μL·min−1·mg−1 protein) | CLint (mL·min−1·kg−1) | Extrapolated CLH (mL·min−1·kg−1) | Observed CLHa (mL·min−1·kg−1) |
|---|---|---|---|---|---|
| Rat | 13.9 | 99.8 | 172 | 49.7 | 50.5 |
| Dog | 83.5 | 16.6 | 31.7 | 17.7 | 23.1 |
| Human | 41.0 | 33.8 | 27.8 | 11.6 | / |
aBlood CL calculated from measured plasma CL and Rbp.
