Table 1. Demographic and clinical data of the subjects and the influence of PPI on their samples.
| Whole | Subjects treated with PPI | Difference between + and − P value | ||
|---|---|---|---|---|
| + | − | |||
| Number of subjects | 45 | 18 | 27 | |
| Age (years) | 48.4±17.3a | 64.4±12.2 | 37.8±10.7 | <0.001 |
| M/F | 32/13 | 12/6 | 20/7 | NS |
| Daily intake of fermented foods (+/−) | 32/13 | 14/4 | 18/9 | NS |
| Saliva | ||||
| Volume collected (ml) | 5.0b (3.5–7.4)c | 5.0 (4.5–8.4) | 5.0 (4.3–6.0) | NS |
| pH | 7.75 (7.45–8.03) | 7.90 (7.52–8.65) | 7.69 (7.52–7.79) | 0.037 |
| Gastric fluid | ||||
| Volume collected (ml) | 14.0 (7.5–21.0) | 11.0 (9.1–14.8) | 17.8 (13.3–21.5) | NS |
| pH | 1.90 (1.38–5.53) | 3.24 (2.87–5.59) | 1.58 (1.66–3.39) | 0.018 |
| Bacterial count by culturing method (log10 CFU/ml) | 5.5±2.7 | 7.2±1.8 | 4.4±2.5 | <0.001 |
| Serum | ||||
| Gastrin (pg/ml) | 87 (75.5–215.0) | 290 (199–426) | 77 (73–98) | <0.001 |
| Anti-H. pylori Ab (+/−) | 6/45 | 3/15 | 3/24 | NS |
Ab, antibody; CFU, colony-forming unit; NS, not significant; PPI, proton-pump inhibitor.
a
Mean±s.d.
b
Median.
c
Interquartile range.