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| Weakly acidic reflux | Residual acidic reflux | Functional heartburn | |
|---|---|---|---|
| Lifestyle modifications | ✓ | ✓ | |
| Compliance/adherence | ✓ | ✓ | |
| Baclofen | ✓ | ✓ | |
| Endoscopic treatment | ✓ | ✓ | |
| Anti-reflux surgery | ✓ | ✓ | |
| Sucralfate | ✓ | ✓ | |
| Gaviscon | ✓ | ✓ | |
| H2RA | ✓ | ||
| Pain modulators | ✓ | ✓ | |
| Psychological intervention | ✓ |
H2RA, histamine-type-2 receptor antagonist; PPI, proton pump inhibitor.
