Table 1. Reasons for exclusion of potentially eligible papers that were considered for the dietary intervention in IBS systematic review.
Reference | Randomized | Design | Dietary intervention | Control | IBS symptoms assessed | Dichotomous data extractable | ≥7 Days therapy |
---|---|---|---|---|---|---|---|
King et al.13 | Yes | Crossover | Exclusion diet | Yes | Yes | No | Yes |
Ong et al.14 | Yes | Crossover | Low FODMAPs diet | Yes | Yes | No | No |
Bentley et al.15 | Yes | Crossover | Exclusion diet after sensitivity testing | Yes | Yes | No | Unclear |
Carroccio et al.16 | Yes | Crossover | Empirical exclusion diet followed by sensitivity testing | Unclear | Yes | No | Yes |
Shepherd et al.17 | Yes | Crossover | Low FODMAPs | Yes | Yes | No | Yes |
Vazquez Roque et al.18 | Yes | Parallel | Gluten-free diet | Yes | No | No | Yes |
Halmos et al.19 | Yes | Crossover | Low FODMAPs | Yes | Yes | No | Yes |
Biesiekierski et al.20 | Yes | Crossover | Rechallenge of gluten after low FODMAPs diet | Yes | Yes | No | No |
Berg et al.21 | Yes | Parallel | Fructose-reducing diet | “IBS diet”—unclear if this is another active therapy | Yes | No | Yes |
Jones et al.22 | Yes | Crossover | Food rechallenge in food elimination responders | Yes | Yes | No | No |
Carroccio et al.23 | No | No | Gluten challenge in wheat-sensitive patients | No | No | No | Yes |
Lunardi et al.24 | Yes | Crossover | Oral chromoglycate in food-intolerant IBS patients—not an eligible intervention | Yes | Yes | No | Yes |
Stefanini et al.25 | Yes | Parallel | Empirical food elimination diet | Sodium chromoglygate—not an eligible control | Yes | Yes | Yes |
Piccinini et al.26 a | Yes | Parallel | Empirical food elimination diet | Sodium chromoglygate—not an eligible control | Yes | Yes | Yes |
FODMAPs, Fermentable Oligo-Di-Monosaccharides and Polyols; IBS, irritable bowel syndrome.
Possible duplicate paper as design similar, but intervention was for 3 weeks rather than 4 weeks.