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. 2016 Mar 31;12(3):e1005477. doi: 10.1371/journal.ppat.1005477

Fig 4. ET-1 contributes to persistent neurological deficits following successful treatment of ECM.

Fig 4

Novel object recognition test of working memory was performed on uninfected and PbA-infected saline or BQ123 treated mice 10 and 40 days post artemether treatment (dpt). (A) Preference scores at 10 dpt; One-way ANOVA, with Tukey’s analysis; ** = p < 0.01, * = p < 0.05. (B) 10 dpt. Percentage of mice that preferentially explored novel object; Chi-square; **** = p < 0.0001. (C) 40 dpt. Preference scores at 40 dpt; One-way ANOVA, with Fisher's LSD analysis; ** = p < 0.01, * = p < 0.05. (D) Percentage of mice that preferentially explored novel object; Chi-square; **** = p < 0.0001. N = 8–12/group