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. 2016 Mar 31;12(3):e1005477. doi: 10.1371/journal.ppat.1005477

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© 2016 Freeman et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 9 — Visual memory testing was performed on PbN-infected (non-CM) and PbN-infected ET-1 treated mice. Non-CM mice do not display visual memory impairments (A,B). (B) A significantly higher proportion of PbN mice passed the object recognition test when compared to PbA mice (p < 0.0001). (A) Exogenous ET-1 treatment induced cognitive dysfunction in PbN-infected mice (p < 0.05). (B) In addition, PbN ET-1 treated mice performed significantly worse than PbN saline treated mice (p < 0.0001). One-way ANOVA was performed for preference scores in A, and Chi-square was performed for success rate in B. n = 4–20/group.