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. 2016 Mar 31;11(3):e0152538. doi: 10.1371/journal.pone.0152538

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© 2016 Elisia et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — (A) The effect of DMSO on melanin production in B16/F10 melanoma cells. *denotes significant difference (P<0.05) in melanin content to non-DMSO treated cells (B) The effect of topical administration of 70% DMSO on the growth of subcutaneously implanted B16/F10 melanoma cells in C57BL/6 mice (n = 8) (C) The effect of DMSO on murine M2 mФ skewing in response to 10 ng/ml IL-4 measured after 72 h of incubation (D) The effect of DMSO in modulating iNOS expression and (E) NO production from M1-skewed murine mФs, measured after 24 h of incubation of cells with 100 ng/mL LPS.