Figure 8.
(A) Schematic diagram showing the synthesis of MN-EPPT-siBIRC5. (B) Representative pre-contrast images and 24 h post-contrast T2-weighted images (top), and color-coded T2 maps (bottom) of the tumor-bearing mice i.v. injected with MN-EPPT-siBIRC5 (10 mg/kg Fe). (C) Relative tumor volume measurements of MN-EPPT-siBIRC5- and MN-EPPT-siSCR-injected animals over the course of treatment. Reprinted with permission from [212], M. Kumar, et al., Image-guided breast tumor therapy using a small interfering RNA nanodrug. Cancer Res. 70, 7553 (2010). © 2010, Cancer Research.