Table 1. Prevalence of Pfcrt and Pfmdr1 alleles before and after treatment with AL % (n/N).
Gene | Genotype profile | Pre-Treatment | Recrudescence | P-value | New infection | P-value |
---|---|---|---|---|---|---|
Pfcrt | K76 | 78.20 (226/289) | 93.33 (56/60) | <0.00001 | 87.95 (73/83) | 0.0487 |
76T | 21.80 (63/289) | 6.67 (4/60) | 12.05 (10/83) | |||
Pfmdr1 | N86 | 91.69 (276/301) | 95.65 (66/69) | 0.2621 | 95.18 (79/83) | 0.2868 |
86Y | 8.31 (25/301) | 4.35 (3/69) | 4.82 (4/83) | |||
Pfmdr1 | Y184 | 50.18 (140/279) | 55.74 (34/61) | 0.4313 | 41.25 (33/80) | 0.1588 |
184F | 49.82 (139/279) | 44.26 (27/61) | 58.75 (47/80) |