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. 2016 Mar 31;11(3):e0152064. doi: 10.1371/journal.pone.0152064

Fig 1. (-)-Epigallocatechin gallate (EGCG) prevented β-sheet-rich amyloidogenesis of lipofuscin (LF).

Fig 1

(A) Effect of EGCG on LF formation as measured by emission of LF-like fluorescence intensity at 460 nm in MDA-modified HSA artificial LF (1 mg/mL) reaction system. (B) Effect of EGCG on LF β-sheet-rich structure formation by measuring Thioflavin T (ThT) fluorescence emission at 485 nm. (C) Analysis of sample aggregation reactions by transmission electron microscopy (TEM) in different groups after 96 h of incubation. Scale bars represent 100 nm. Data are expressed as means ± SD, n = 3.