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. 2016 Mar 31;11(3):e0152368. doi: 10.1371/journal.pone.0152368

Fig 3. Correlation analysis of clinico-pathological features of HSPN patients, based on the percentages of CD19+ B cell subtypes.

Fig 3

(A) The eGFR was negatively correlated with the number of CD38+CD19+ B cells. (B) The eGFR was positively correlated with the numbers of IL-10+CD19+ B cells, (C) CD1d+CD5+CD19+ B cells (D), and IL-10+CD1d+CD5+CD19+ B cells (E) as well as the serum concentration of IL-10. (F) The 24-h urinary protein concentration was positively correlated with the number of CD38+CD19+ B cells. (G) The 24-h urinary protein concentration was negatively correlated with the numbers of IL-10+CD19+ B cells, (H) CD1d+CD5+CD19+ B cells, and (I) IL-10+CD1d+CD5+CD19+ B cells as well as the (J) serum concentration of IL-10. The potential correlations among the numbers of B cells of different subsets, Bregs, and the values of clinical parameters were analyzed by the Spearman correlation tests.