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. 2016 Mar 31;11(3):e0152581. doi: 10.1371/journal.pone.0152581

Fig 2. β-PEA and tyramine stimulate recombinant B6 but not D2 mTAAR1.

Fig 2

The endogenous ligands, β-PEA (A) and tyramine (B) elicited a dose-dependent response in mammalian cells expressing recombinant B6-like, but not the D2-like (P77T) mTAAR1. Dose-response curves for the recombinant B6-like receptor were shifted to the right by EPPTB (10 μM). β-PEA EC50 = 0.547± 0.03 μM; Tyramine EC50 = 0.940 ± 0.12 μM. LSD has no effect on either receptor (C).