Table 2. Characteristics of study population at visit 12 by FSH groups.
| Characteristics | Low FSH N=53 | Medium FSH N=431 | High FSH N=372 | P value |
|---|---|---|---|---|
| Age, years, Mean(SD) | 58.66 (2.50) | 59.17 (2.54) | 59.97 (2.76) | <0.001 |
| Race, n (%) | <0.001 | |||
| Black | 27 (50.94) | 144 (33.41) | 92 (24.73) | |
| White | 16 (30.19) | 201 (46.64) | 183 (49.19) | |
| Chinese | 1 (1.89) | 62 (14.39) | 78 (20.97) | |
| Hispanic | 9 (16.98) | 24 (5.57) | 19 (5.11) | |
| Education, n (%) | 0.09 | |||
| ≤ High school/some college | 32 (61.54) | 242 (56.54) | 183 (49.86) | |
| College degree/post college | 20 (38.46) | 186 (43.46) | 184 (50.14) | |
| BMI, kg/m2, Mean (SD), | 37.63 (9.07) | 30.75 (7.34) | 27.30 (6.11) | <0.001 |
| SBP, mmHg, Mean (SD) | 129.77 (14.91) | 122.27 (17.95) | 119.75 (17.42) | 0.0003 |
| DBP, mmHg, Mean (SD) | 76.61 (10.33) | 74.41 (9.99) | 73.09 (10.53) | 0.03 |
| HDL-C, mg/dL, Mean (SD) | 52.98 (12.06) | 60.60 (15.50) | 65.51 (16.22) | <0.001 |
| LDL-C, mg/dL, Mean (SD) | 106.94 (28.32) | 120.06 (32.64) | 122.84 (30.54) | 0.003 |
| Triglycerides, mg/dL, Median (Q1, Q3) | 110.00 (89.00, 146.00) | 98.00 (74.00, 140.00) | 88.00 (68.00, 124.00) | 0.001 |
| HOMA index, Median (Q1, Q3) | 3.94 (2.22, 7.08) | 2.44 (1.33, 3.99) | 1.61 (1.06, 3.03) | <0.001 |
| Physical activity score,* Mean (SD) | 7.06 (1.78) | 7.56 (1.85) | 7.67 (1.88) | 0.08 |
| Diabetes, n (%) | 13 (24.53) | 57 (13.23) | 23 (6.18) | <0.001 |
| Ever Smoker, n (%) | 17 (50.00) | 167 (47.99) | 128 (42.67) | 0.35 |
| Ever use of medications,† n (%) | 39 (79.59) | 249 (64.18) | 177 (55.49) | 0.002 |
| Mean-IMT, mm, Mean (SD) | 0.79 (0.09) | 0.81 (0.13) | 0.77 (0.11) | 0.001 |
| Maximal-IMT, mm, Mean (SD) | 0.92 (0.09) | 0.94 (0.15) | 0.90 (0.13) | 0.0001 |
| AD, mm, Mean (SD) | 7.32 (0.71) | 7.21 (0.67) | 7.11 (0.62) | 0.02 |
| Presence of plaque, n (%) | 17 (32.08) | 197 (45.81) | 163 (43.82) | 0.16 |
| Time since FMP, year, Mean (SD) | 7.92 (3.89) | 7.41 (3.21) | 8.59 (3.06) | <0.001 |
| Ever use hormone therapy, n (%) | 1 (1.89) | 20 (4.64) | 22 (5.91) | 0.40 |
*
Higher scores indicating more physical activity
†
Antihypertensive, antidiabetic, lipid lowering, or anticoagulants medications