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. Author manuscript; available in PMC: 2016 Apr 19.
Published in final edited form as: Hepatol Res. 2015 Jul 14;46(4):306–311. doi: 10.1111/hepr.12545

Figure 4. Histological features of the liver in a child with biallelic mutations in both ATP8B1 and ABCB4.

Figure 4

Hematoxylin/eosin staining of a liver biopsy obtained at the time of diagnosis and genetic testing of a child with intrahepatic cholestasis carrying biallelic mutations in ATP8B1 portal-to-portal fibrosis (arrows); the middle panel and right panels show bile duct proliferation (arrows) and mild portal inflammation (yellow arrows).