Table 1.
pH Dependence of Cross Peaks and Correlation with Conductance Domain Structure PDB: 2L0J
| Residues Involved | Distance Range in PDB: 2L0J (Å) | pH 7.5 Cross Peaks Observed | pH 7.5 Agreement with PDB: 2L0J Distances | pH 7.5 Cross Peaks Observed |
|---|---|---|---|---|
| Leu26Cα-Val28Cα | 8.1–8.2 | — | + | + |
| Ala30Cα-Ile35Cγ2 | 3.6–3.9 | + | + | — |
| Leu26Cα-Ile32Cα | 7.5–8.1 | +b | +b | +b |
| Leu38Cα-Ile33Cα | 7.7–8.2 | +b | +b | +b |
| Leu46Cγ-Phe54Cδε | 4.6–7.0a | +c | +c | +c |
| Leu59Cγ-Phe48Cδε | 5.2–6.7a | +c | +c | +c |
| Leu46Cγ-Phe54Cγ | 6.4–7.4a | +d | +c | +c |
| Leu59Cγ-Phe48Cγ | 5.0–5.7a | +c | +c | +c |
| L59V Leu46Cγ-Phe54Cδε | 4.6–7.0a | + | + | — |
| L59V Leu46Cγ-Phe54Cγ | 6.4–7.4a | — | — | — |
a
Measured range for three out of four residue pairs in the PDB: 2L0J WT protein.
b
The observed interaction could be the result of a short distance for either of these two Leu/Ile pairs.
c
The observed interaction could be the result of a short distance for either of these two Leu/PheCde pairs.
d
The observed interaction could be the result of a short distance for either of these two Leu/PheCg pairs.