Table 4.
Multiethnic APOL1 Genotype Frequencies
| APOL1 genotype | African American (n = 5453) |
Hispanic (n = 1146) |
Asian (n = 460) |
|||
|---|---|---|---|---|---|---|
| Observed, % | Expected, %∗ | Observed, % | Expected, %∗ | Observed, % | Expected, %∗ | |
| c.1072A>G | ||||||
| A/A | 62.6 (n = 3411) | 61.5 | 92.8 (n = 1063) | 92.8 | 97.4 (n = 448) | 97.4 |
| A/G | 31.7 (n = 1732) | 33.8 | 7.2 (n = 82) | 7.1 | 2.6 (n = 12) | 2.6 |
| G/G | 5.7 (n = 310) | 4.7 | 0.1 (n = 1) | 0.1 | 0.0 (n = 0) | 0.0 |
| c.1200T>G | ||||||
| T/T | 63.2 (n = 3448) | 62.2 | 92.8 (n = 1064) | 92.9 | 97.4 (n = 448) | 97.4 |
| T/G | 31.3 (n = 1705) | 33.3 | 7.1 (n = 81) | 7.0 | 2.6 (n = 12) | 2.6 |
| G/G | 5.5 (n = 300) | 5.5 | 0.1 (n = 1) | 0.1 | 0.0 (n = 0) | 0.0 |
| c.1212_1217del6 | ||||||
| TTATAA/TTATAA | 75.9 (n = 4139) | 75.6 | 95.0 (n = 1089) | 95.0 | 99.1 (n = 456) | 99.1 |
| TTATAA/del | 22.1 (n = 1207) | 22.7 | 4.9 (n = 56) | 4.9 | 0.9 (n = 4) | 0.9 |
| del/del | 2.0 (n = 107) | 1.7 | 0.1 (n = 1) | 0.1 | 0.0 (n = 0) | 0.0 |
∗
Predicted Hardy-Weinberg frequencies.