Figure 7.

Phase comparisons of peak Per1, Per2, and Bmal1 mRNA diurnal expression within the PFC (most typical timing across all subregions is depicted) (Supplemental Figure 2) and SCN of each treatment group in experiments 1 and 2. Circles are oriented as clock faces with ZT labels, and shading of the dark phase. Time of peak expression is shown only where a significant effect of time of death was observed (Tables 1 and 2). Note in the SCN the lack of effect of CORT manipulations on clock gene expression phase relationships, but in the PFC the dramatic effect relative to sham rats of all manipulations except daily in-phase CORT treatment of ADX rats.