. 2016 Feb 22;157(4):1522–1534. doi: 10.1210/en.2015-1884

Table 2.

Experiment 2

Experiment 2. Rat Clock Gene Expression Two-Way ANOVA Results					Peak ZT for CORT Status Groups With Significant Effect of Time of Death (P < .05, One-Way ANOVA)
Gene	ROI	Time of Death	CORT Status	Time of Death × CORT Status	ADX + In-Phase CORT	ADX + Veh	ADX + Antiphasic CORT
Per1	ACC	F_3,52 = 5.8^a	F_2,52 = 3.6^a	F_6,52 = 4.7^a	ZT12	(P = .06)	(P =.5)
	PL	F_3,58 = 7.8^a	F_2,58 = 5.1^a	F_6,58 = 5.3^a	ZT18	(P = .05)	(P = .7)
	IL	F_3,53 = 8.5^a	F_2,53 = 13.3^a	F_6,53 = 6.6^a	ZT18	ZT6/18	(P = .4)
	VO	F_3,58 = 7.9^a	F_2,58 = 3.3^a	F_6,58 = 5.5^a	ZT12	ZT18	(P = .7)
	SCN	F_3,67 = 165.2^a	F_2,67 = 2.0	F_6,67 = 2.9^a	ZT6	ZT6	ZT6
Per2	ACC	F_3,53 = 6.1^a	F_2,53 = 7.2^a	F_6,53 = 6.5^a	ZT12	ZT18	(P = .3)
	PL	F_3,55 = 1.5	F_2,55 = 4.5^a	F_6,55 = 2.8^a	(P = .07)	ZT18	(P = .3)
	IL	F_3,56 = 1.4	F_2,56 = 4.5^a	F_6,56 = 5.3^a	ZT12	ZT18	ZT0
	VO	F_3,54 = 9.9^a	F_2,54 = 3.5^a	F_6,54 = 6.3^a	ZT12	ZT18	ZT0
	SCN	F_3.67 = 194.4^a	F_2,67 = 0.04	F_6,67 = 1.1	ZT6	ZT6	ZT6
Bmal1	ACC	F_3,61 = 4.5^a	F_2,61 = 0.11	F_6,61 = 4.2^a	ZT0	ZT18	(P = .4)
	PL	F_3,60 = 2.3^a	F_2,60 = 0.28	F_6,60 = 4.3^a	ZT0	ZT18	(P = .5)
	IL	F_3,62 = 2.4	F_2,62 = 0.29	F_6,62 = 5.5^a	ZT0	ZT18	(P = .1)
	VO	F_3,61 = 8.7^a	F_2,61 = 0.49	F_6,61 = 7.9^a	ZT0	ZT18	(P = .4)
	SCN	F_3,67 = 52.8^a	F_2,67 = 1.3	F_6,67 = 2.8^a	ZT12	ZT12	ZT12

Two-way ANOVA and one-way ANOVA results for clock gene expression in the PFC (ACC, PL, IL, and VO) and SCN. Factors were time of death (ZT0, ZT6, ZT12, or ZT18) and CORT status (ADX+vehicle, ADX+in-phase CORT, and ADX+antiphasic.

P < .05.