Table 5.

Group fMRI connectivity results for each seed region

Cluster no.	Side	Region(s)	Size (mm3)	Peak MNI coordinates
				x	y	z	z-score
Right cereb lobule I–IV seed
Control versus ET
Cluster 1	Con	PMv*	675	−54	15	30	5.20
Cluster 2	Con	M1*	648	−36	−24	60	4.68
Cluster 3	Con	PMd*	459	−36	−6	63	4.26
Cluster 4	Ipsi	PMd*	378	24	9	63	4.21
Cluster 5	Con	M1*	324	−45	−9	57	4.17
Cluster 6	Ipsi*, Con	SMA	351	3	−18	66	−4.20
	Con	M1
ET versus PD
Cluster 1	Con	M1*	351	−36	−27	66	−3.40
Left M1 seed
Control versus ET
Cluster 1	Ipsi*, Con	Pre-SMA*, SMA	7533	12	12	51	−6.23
	Con	PMd
Cluster 2	Con	S1*	324	−48	−27	48	−5.33
Cluster 3	Con	M1*, PMd	1107	−33	−12	54	−4.88
Cluster 4	Con	S1*, M1	1485	−30	−30	51	−4.83
Cluster 5	Con	S1*	324	−54	−27	42	−4.35
Control versus PD
Cluster 1	Con	M1*	405	−51	−12	54	−3.88
ET versus PD
Cluster 1	Con	SMA*	351	−6	−12	72	4.49
Cluster 2	Ipsi*, Con	Pre-SMA	540	3	12	51	4.34
SMA seed
Control versus ET
Cluster 1	Ipsi	PMv*	351	51	3	24	5.00
Cluster 2	Con	PMd*, pre-SMA, SMA	1890	−18	6	51	−5.49
Cluster 3	Con	M1*	459	−48	−6	63	−4.98
Cluster 4	Ipsi	M1*, PMd	540	33	−12	45	−4.62
Cluster 5	Con	SMA*	837	−9	−15	60	−4.54
ET versus PD
Cluster 1	Con	M1*, S1	594	−30	−30	57	4.32

Note : Con, contralateral; ET, essential tremor; Ipsi, ipsilateral; M1, primary motor cortex; PMd, dorsal premotor area; PMv, ventral premotor area; S1, primary somatosensory cortex; SMA, supplementary motor area. All clusters significant at P < 0.05, corrected. Region at peak coordinate is noted with an asterisk. Only significant effects are reported in the table.