Table 1. Properties of PET perfusion tracers10,11 .
15O-water | 13N-ammonia | 82Rb | 18F-flurpiridaz | |
Half-life | 2 min | 10 min | 76 s | 109 min |
Cyclotron on-site needed | Yes | Yes | No | No |
Average positron energy (MeV) | 0.74 | 0.49 | 1.48 | 0.25 |
RMS positron range (mm) | 1.0 | 0.6 | 2.6 | 0.2 |
Positron range | 4.1 | 2.5 | 8.6 | 1.0 |
Myocardial extraction fraction | 100 | 80 | 65 | 94 |
Image quality | Poor | Excellent | Good | Excellent |
Image interpretation | No | Yes | Yes | Yes |
Quantification of myocardial blood flow | Yes | Yes | Yes | Yes |
Stress modality | Pharmacologic | Pharmacologic or exercise (feasible but not practical) | Pharmacologic | Pharmacologic or exercise |
PET, positron emission tomography; RMS, root-mean square.