Table 3. Prevalence of ECG abnormalities among children with SCA and age- and gender-matched haemoglobin AA controls.
ECG abnormalities | Cases n (%) | Controls n (%) | p-value | Odds ratio (95% CI) |
Sinus arrhythmia | 5 (8.1) | 4 (10.0) | 0.737 | 0.8 (0.2–3.1) |
Sinus rhythm with ventricular premature complex | 1 (1.6) | 0 (0) | 1.000 | 2.0 (0.1–47.9) |
Right atrial enlargement | 3 (4.8) | 0 (0) | 0.417 | 1.7 (1.4–2.0) |
Left ventricular hypertrophy | 44 (71.0) | 11 (27.5) | 0.000 | 6.4 (2.7–15.6) |
Right ventricular hypertrophy | 5 (8.1) | 1 (2.5) | 0.462 | 3.4 (0.4–30.4) |
Biventricular hypertrophy | 3 (4.8) | 0 (0) | 0.158 | 1.7 (1.4–2.0) |
ST-segment elevation | 3 (4.8) | 3 (7.5) | 0.899 | 0.6 (0.1–3.2) |
ST depression | 4 (6.5) | 0 (0) | 0.264 | 1.7 (1.4–2.0) |
Tall T-wave anomaly | 1 (1.6) | 0 (0) | 1.000 | 1.9 (0.1–47.9) |
T-wave abnormality consistent with lateral ischaemia | 8 (12.9) | 0 (0) | 0.021 | 12.6 (1.7–21.7) |
Non-specific T-wave abnormalities | 4 (6.5) | 1 (2.5) | 0.646 | 2.7 (0.3–24.3) |
Right ventricular conduction delay | 1 (1.6) | 0 (0) | 1.000 | 2.0 (0.1–47.9) |
Non-specific intraventricular conduction block | 2 (3.2) | 0 (0) | 0.519 | 3.4 (0.2–69.1) |
Abnormal left-axis deviation | 1 (1.6) | 2 (5.0) | 0.559 | 0.3 (0.1–3.5) |
First-degree atrio-ventricular block | 12 (19.4) | 0 (0) | 0.008 | 1.8 (1.5–2.2) |
Presence of at least one abnormality on ECG findings | 49 (79.0) | 18 (45.0) | 0.000 | 4.6 (1.9–10.9) |