Table 1.
Baseline demographic and clinical characteristics of study participants
| All participants (n = 129) |
Venlafaxine group (n = 65) |
Lithium group (n = 64) |
Pa | |
|---|---|---|---|---|
| Women,a n (%) | 73 (56.6) | 35 (53.8) | 38 (59.4) | 0.60 |
| Racial or ethnic minority,a n (%) | 26 (20.2) | 9 (13.8) | 17 (26.6) | 0.08 |
| Rapid cycling,a n (%) | 55 (42.6) | 30 (46.2) | 25 (39.1) | 0.48 |
| Inter-episode recovery,a n (%) | 28 (21.7) | 13 (20.0) | 15 (23.4) | 0.92 |
| Age,b mean (s.d) | 42.9 (13.6) | 43.0 (13.1) | 42.7 (14.3) | 0.92 |
| Age first major depressive episode, years:b mean (s.d) | 17.9 (7.3) | 18.6 (7.7) | 17.2 (7.0) | 0.28 |
| Age first hypomanic episode,b mean (s.d) | 20.5 (9.3) | 20.6 (8.0) | 20.5 (10.7) | 0.92 |
| Number of prior major depressive episodes,b mean (s.d) | 24.0 (37.4) | 24.1 (42.2) | 24.0 (32.3) | 0.99 |
| Number of prior hypomanic episodes,b mean (s.d) | 44.2 (81.7) | 43.9 (61.0) | 44.4 (99.1) | 0.97 |
| Baseline Hamilton Rating Scale for Depression,13 mean (s.d) | 20.1 (3.8) | 20.0 (3.7) | 20.2 (3.8) | 0.64 |
| Baseline Young Mania Rating Scale,3 mean (s.d) | 0.5 (0.4) | 0.6 (1.4) | 0.5 (1.4) | 0.93 |
| Duration of depressive episode, months:c median | 6.0 | 5.0 | 6.8 | 0.34 |
a.
P-values are from Fisher's exact test.
b.
P-value for comparison of means from independent samples t-test
c.
P-value for comparison of medians from independent samples.