Figure 5. Effects of 1,3-DCP on NF-κB-related inflammatory mediators and cytokines. (A) Immunoblotting analysis of TNF-α, Cox-2, and iNOS expression and (B) its relative protein levels in the male rats treated with 1,3-DCP (loading control: β-actin). The bar graphs show relative mRNA levels of NF-κB-related inflammatory mediator or cytokine, (C) iNOS, (D) Cox-2, (E) TNF-α, (F) IL-1β, and (G) IL-6 mRNA levels for 1,3-DCP-treated rat (loading control: GAPDH). Values are presented as mean±SD (n=6). ^**P<0.01 versus control group. 1,3-DCP: 1,3-dichloro-2-propanol; NF-κB: nuclear factor-kappa B; TNF-α: tumor necrosis factor-alpha; Cox-2: cyclooxygenase-2; iNOS: inducible nitric oxide synthase; IL-1β: interleukin-1β; IL-6: interleukin-6; and GAPDH: glyceraldehydes-3-phosphate dehydrogenase.