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. 2016 Mar 24;32(1):24–33. doi: 10.5625/lar.2016.32.1.24

Table 3. Lipid peroxidation, glutathione concentration, and antioxidant enzyme activities in the liver of male rats treated with 1,3-DCP.

Items 1,3-DCP (mg/kg)
0 27.5 55 110
No. of rats 6 6 6 6
MDA (nmol/mg protein) 0.49±0.02a 0.52±0.05 0.58±0.05** 0.64±0.04**
GSH (nmol/mg protein) 3.89±0.29 3.61±0.24 3.13±0.56** 2.88±0.39**
Catalase (units/mg protein) 50±11 38±9* 35±5** 34±6.0**
GR (units/mg protein) 0.72±0.06 0.58±0.07** 0.50±0.05** 0.49±0.04**
GST (units/mg protein) 154±14 111±13** 92±18** 53±17**

aValues are expressed as mean±SD. *P<0.05 versus control group. **P<0.01 versus control group.

1,3-DCP: 1,3-dichloro-2-propanol; MDA: malondialdehyde; GSH: reduced glutathione; GR: glutathione reductase; and GST: glutathione S-transferase.