TABLE 1.
B. melitensis LPS mutants used in the present work
Name | Parental strain | Gene (ORF) | Role (annotation) | LPS phenotype | Refs. |
---|---|---|---|---|---|
Bm_manBcore | H38 | manBcore (BMEII0899) | Core synthesis (phosphomannomutase ) | R3 | 10 |
Bm_wbkD | H38 | wbkD (BMEI1427) | O-PS synthesis (epimerase/dehydratase) | R1 | 10 |
Bm_per | 16M | per (BMEI1414) | O-PS synthesis (perosamine synthetase) | R1 | 10, 46, 47 |
Bm_wadC | 16M | wadC (BMEI0509) | Core synthesis (glycosyltransferase) | S | This work |
Bm_wadC_per | 16M | wadC (BMEI0509)/per (BMEI1414) | Core and O-PS synthesis | R3 | This work |