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Hepatic cDCs isolated from S. mansoni-infected mice support effector/memory CD4+ T-cell proliferation and cytokine production. Proliferation and cytokine profiles of pre-activated effector/memory OT-II CD4+ T cells in response to presentation of OVA323-339 peptide (a, b) or soluble OVA protein (c, d) by cDCs isolated from the livers of naïve or infected mice (6 weeks post infection). Data are pooled from three experiments. Error bars indicate mean±s.e.m.
