FIG 7 .

Catalytically active MERS-CoV NS4b rescues replication of MHV^Mut in the livers of B6 mice. Liver titers (n = 19 or 20) day 5 postinfection (MOI of 2,000 PFU) of MHV^WT and MHV^Mut (A) or MHV-MERS^WT and MHV-MERS^Mut (B). Statistical significance was determined by χ² test with Yates’ correction and is indicated as follows: *, P  value of <0.05; ***, P < 0.001. Values are means ± SEM (error bars). Values that are not significantly different (ns) are indicated. These data are pooled from four experiments