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. 2016 Mar-Apr;22(2):133–138. doi: 10.4103/1319-3767.167186

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Copyright: © Saudi Journal of Gastroenterology

This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Phylogenetic tree of representative HBV strains: S gene sequence of 5 Saudi and 30 international HBV strains was aligned using Megalign program of Lasergene software (DNASTAR) and tree was constructed via the neighborhood-joining method of MEGA 5.1 program. Confidence of the tree was verified by bootstrapping for 1000 times and only percentages above 50% were denoted at the branch nodes. Genotypes and subgenotypes are indicated at the right side of the tree. HBV strains were classified into 8 genotypes A–H, whereas genotype D in further divided into 5 subgenotypes D1–D5. All viral strains in Saudi Arabia are categorized within genotype D in both subgenotypes D1 and D3