Table 1.

Comparison of the predictive power of baseline and follow-up NIHSS measurements for 3-month good clinical outcome

Variable	IMS3	NINDS tPA
Predictive power for 3-month mRS 0–2
24-hour NIHSS	0.91	0.922
NIHSS improvement in 24 h (24 h – baseline)	0.83	0.76
Relative improvement in NIHSS over 24 h	0.87	0.83
Baseline NIHSS	0.73	0.78
2-hour NIHSS	n.a.	0.85
Predictive power for 3-month BI ≥95
24-hour NIHSS	0.9	0.9
NIHSS improvement in 24 h (24 h – baseline)	0.84	0.76
Relative improvement in NIHSS over 24 h	0.87	0.83
Baseline NIHSS	0.66	0.75
2-hour NIHSS	n.a.	0.82

n.a. = Not available.