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(A) Biodistribution of solithromycin in pregnant sheep, showing concentrations in the maternal, fetal, and amniotic fluid (AF) compartments after maternal intravenous administration (10 mg/kg); (B) Plasma and AF concentration data in the same model after intra-amniotic injection (1.4 mg/kg fetal weight); azithromycin and solithromycin data taken from Ref (82).
