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C5aRA treatment decreases CCR5 expression by THP-1 or MDM. Differentiated THP-1 (a) or MDM (b) were treated with C5aRA (87.4 μM) for the indicated times. CCR5 or C5aR1 expression (MFI) was determined by flow cytometry. The graph shows mean normalized levels (MFI at time 0 was considered as 100% expression) (n = 3).
