Figure 1.

Simplified illustration of thiamin metabolism in Ca. P. ubique. Black colored lines and enzyme abbreviations represent reactions and enzymes encoded by the Ca. P. ubique genome. Red colored lines and enzyme abbreviations represent reactions and enzymes that are absent from the Ca. P. ubique genome. AIR, aminoimidazole ribotide; AmMP, 4-amino-5-aminomethyl-2-methylpyrimidine; cys, cysteine; dDXP, 1-deoxy-D-xylulose 5-phosphate; gly, glycine; his, histidine; HMP(-P), 4-amino-5-hydroxymethyl-2-methylpyrimidine (-phosphate); HMP-PP, 4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphate; ThP, thiamin monophosphate; ThPP, thiamin diphosphate; THZ-P, 4-methyl-5-(2-phosphoethyl)-thiazole.