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. Author manuscript; available in PMC: 2016 Dec 1.

Published in final edited form as: Atherosclerosis. 2015 Oct 24;243(2):533–539. doi: 10.1016/j.atherosclerosis.2015.10.095

Table 4. Multivariable analyses of complement proteins with presence of calcification.

	Presence of CAC^a		Presence of AC^a

		C3
	OR (95%CI)^b	P-value	OR (95%CI)^b	P-value
Unadjusted	2.64 (1.58-4.42)	<0.001	2.19 (1.32-3.64)	0.003
Model 1^c	2.32 (1.33-4.03)	0.003	1.97 (1.13-3.43)	0.016
Model 2^c	1.90 (1.07-3.39)	0.029	1.76 (0.98-3.16)	0.056
Model 2 + TAT^d	1.47 (0.744-2.93)	0.265	1.06 (0.52-2.15)	0.876
Model 2 + PVAT^d	1.31 (0.71-2.43)	0.385	1.48 (0.81-2.74)	0.206

		C4

	OR (95%CI)^b	P-value	OR (95%CI)^b	P-value
Unadjusted	1.42 (0.94-2.14)	0.093	1.32 (0.86-2.04)	0.203
Model 1^c	1.36 (0.87-2.11)	0.180	1.20 (0.76-1.91)	0.434
Model 2^c	1.32 (0.83-2.11)	0.244	1.15 (0.71-1.85)	0.572
Model 2 + TAT^d	1.25 (0.72-2.17)	0.435	0.83 (0.47-1.45)	0.511
Model 2 + PVAT^d	1.16 (0.69-1.93)	0.572	1.04 (0.65-1.70)	0.848

^a

CAC>0, AC>0

^b

OR per standard deviation (SD); SD of C3= 33.28 mg/dl, SD of C4= 8.77 mg/dl

^c

Model 1: Adjusted for age, race and menopausal status; Model 2: Model 1+ LDL-C

^d

log transformed