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. 2016 Jan 5;24(2):398–405. doi: 10.1038/mt.2015.216

Figure 3.

Figure 3

Variable protective efficacy of BCG groups. (a) Comparison of effectiveness of BCG groups based on tandem duplication DU2. The data of Figure 2a were redrawn by combining BCG strains of the DU2 same group. One-way analysis of variance (ANOVA) and Bonferroni's multiple comparisons were performed for statistical analysis. **P < 0.01, ***P < 0.001. (b) Comparison of effectiveness of BCG strains based on virulence. The 13 BCG strains were divided into three major groups based on virulence: the most virulent group: BCG-Phipps, BCG-Pasteur, BCG-Tice, and BCG-Frappier; the intermediate virulent group: BCG-China, BCG-Russia, BCG-Moreau, and BCG-Danish; and the least virulent group: BCG-Japan, BCG-Birkhaug, BCG-Sweden, BCG-Glaxo, and BCG-Prague. The data of Figure 2a were redrawn by combining data of the same group. One-way ANOVA and Bonferroni's multiple comparisons were performed for statistical analysis. ***P < 0.001. BCG, Bacille Calmette–Guérin; CFU, colony-forming unit; PBS, phosphate-buffered saline.