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. 2015 Jun 30;23(8):1285–1297. doi: 10.1038/mt.2015.105

Figure 7.

Figure 7

Increased sarcolemmal localization of UGC and α7β1 integrin protein complexes in mdx mice treated with rMsGal-1. Immunoblot analysis of α- and β-dystroglycans (DG), α7A and α7B integrin, utrophin (Utr), α- β-, δ- and ɛ-sarcoglycans (SG), sarcospan (SSPN), and β1D integrin (a). Representative example immunoblots are shown for each protein tested (b–l). All immunoblots were quantified using ImageJ analysis software and were normalized as indicated on graphs (*P < 0.05, **P < 0.01). High-resolution confocal images were taken of transverse sections of tibialis anterior from mdx mice treated with either phosphate-buffered saline or rMsGal-1. Immunofluorescence images show increased correct localization of UGC and α7β1 Integrin proteins (m–z).