Skip to main content
. 2015 Jun 30;23(9):1434–1443. doi: 10.1038/mt.2015.92

Figure 1.

Figure 1

ACE2 expression in the liver and other major organs of healthy C57BL/6 mice treated with rAAV2/8-ACE2 gene therapy. ACE2 expression was evaluated by (a) qPCR, (b) western blotting, and (c) activity assay. rAAV2/8-ACE2 significantly increased liver specific ACE2 mRNA expression, ACE2 protein and activity compared to mice treated with saline injection. Each bar represents the mean ± SEM profile from n = 5 mice per treatment group. *P < 0.0001 and #P < 0.01 were calculated by one-way analysis of variance with Tukey comparison test.