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. 2016 Apr 1;11(4):e0152729. doi: 10.1371/journal.pone.0152729

Fig 2. Non-selective NMDA channel blockers elicit robust changes in gamma (30–55 Hz) qEEG in cynomolgus monkeys.

Fig 2

Y-axis is relative power in gamma (30–55 Hz) frequency band of the EEG power spectrum. X-axis is time after IM or IV administration. Results are the mean ± SEM (N = 5–6). Gamma band after 0.56 mg/kg IV ketamine (solid symbol) differs from vehicle (open symbol) at p < .01 level (Table 1). IM Ketamine (solid symbol) caused an increase in gamma relative power after 3 mg/kg, but was not significantly different from vehicle (open symbol), p>.05 (Table 1). Lanicemine 5.6 mg/kg IM (solid symbol), increases gamma band relative power and differs from vehicle (open symbol) at p < .05 level (Table 1).