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. 2016 Apr 1;10(4):e0004371. doi: 10.1371/journal.pntd.0004371

Table 3. Standard transition probability matrix sets (TPMS) and the datasets used to develop TPMS.

TPMS First round of drug distribution Second round of drug distribution Dataset used to develop standard TPMS no. of school-aged children Comments (assumption) Ref.
TPMS 1 Albendazole Albendazole Viet Nam 366 Calculated form study implementing the intervention [10]
TPMS 2 Mebendazole Mebendazole Tanzania (Zanzibar) 1311 Calculated form study implementing the intervention [11]
TPMS 3 Albendazole No second round intervention Uganda 1423 Calculated form study implementing the intervention [5]
TPMS 4 Mebendazole No second round intervention Tanzania (Zanzibar) 1324 Calculated form study implementing the intervention [12]
TPMS 5 Albendazole + Ivermectin* Albendazole Viet Nam 366 Similar to TPMS1 (slightly more [1013]
Tanzania (Zanzibar) 301 active in hookworms)
TPMS 6 Albendazole + Ivermectin* Mebendazole Viet Nam and 366 Equal to TPMS5 [1011]
Tanzania (Zanzibar) 1311
TPMS 7 Albendazole + Diethylcarbamazine* Albendazole Viet Nam 366 Equal to TPMS1 (absence of impact of DEC on STH) [10]
TPMS 8 Albendazole + Diethylcarbamazine* Mebendazole Tanzania (Zanzibar) 1311 Equal to TPMS2 (absence of impact of DEC on STH) [11]
TPMS 9 Albendazole + Ivermectin* No second round intervention Tanzania (Zanzibar) 301 Calculated form study implementing the intervention [13]
TPMS 10 Albendazole+ Diethylcarbamazine* No second round intervention Uganda 1423 Equal to TPMS3 (absence of impact of DEC on STH) [5]

* Interventions administered to the entire population in a district in the context of the global programme for elimination of lymphatic filariasis; their impact on STH prevalence in the community is larger than the administration of benzimidazoles to children only.