Table 3. Standard transition probability matrix sets (TPMS) and the datasets used to develop TPMS.
TPMS | First round of drug distribution | Second round of drug distribution | Dataset used to develop standard TPMS | no. of school-aged children | Comments (assumption) | Ref. |
---|---|---|---|---|---|---|
TPMS 1 | Albendazole | Albendazole | Viet Nam | 366 | Calculated form study implementing the intervention | [10] |
TPMS 2 | Mebendazole | Mebendazole | Tanzania (Zanzibar) | 1311 | Calculated form study implementing the intervention | [11] |
TPMS 3 | Albendazole | No second round intervention | Uganda | 1423 | Calculated form study implementing the intervention | [5] |
TPMS 4 | Mebendazole | No second round intervention | Tanzania (Zanzibar) | 1324 | Calculated form study implementing the intervention | [12] |
TPMS 5 | Albendazole + Ivermectin* | Albendazole | Viet Nam | 366 | Similar to TPMS1 (slightly more | [10–13] |
Tanzania (Zanzibar) | 301 | active in hookworms) | ||||
TPMS 6 | Albendazole + Ivermectin* | Mebendazole | Viet Nam and | 366 | Equal to TPMS5 | [10–11] |
Tanzania (Zanzibar) | 1311 | |||||
TPMS 7 | Albendazole + Diethylcarbamazine* | Albendazole | Viet Nam | 366 | Equal to TPMS1 (absence of impact of DEC on STH) | [10] |
TPMS 8 | Albendazole + Diethylcarbamazine* | Mebendazole | Tanzania (Zanzibar) | 1311 | Equal to TPMS2 (absence of impact of DEC on STH) | [11] |
TPMS 9 | Albendazole + Ivermectin* | No second round intervention | Tanzania (Zanzibar) | 301 | Calculated form study implementing the intervention | [13] |
TPMS 10 | Albendazole+ Diethylcarbamazine* | No second round intervention | Uganda | 1423 | Equal to TPMS3 (absence of impact of DEC on STH) | [5] |
* Interventions administered to the entire population in a district in the context of the global programme for elimination of lymphatic filariasis; their impact on STH prevalence in the community is larger than the administration of benzimidazoles to children only.