Fig 4. The effect of NaHS on the mRNA expression of cytokines and chemokines in myometrium of the normal pregnant and LPS-induced preterm labor mice.

Mice accepted two i.p. injections of NS or LPS (0.4mg/kg) with or without NaHS (10mg/kg) at 14.5 dpc. The myometrium was harvested when the LPS-injected mice delivered the first pups. The mRNA levels of IL-1β (A), IL-6 (B), TNF-α (C), CCL-2 (D), and CXCL-15 (E) were measured by real-time RT-PCR and normalized by β-actin. Values are presented as mean ± SEM. N = 6 (vehicle and NaHS groups) or 10 (LPS and LPS+NaHS groups). * P<0.05, **P<0.01 compared with vehicle control, #: P<0.05 compared with LPS-injected group.