Table 1.
Brief description of the 13 studies reviewed on ginger for treating nausea and vomiting in pregnancy.
| STUDY | TREATMENT | COMPARATOR | DURATION (DAYS) | MAIN FINDINGS |
|---|---|---|---|---|
| Fischer-Rasmussen, 1991 | 250 mg ginger powder capsules (4 × daily) | Placebo | 4 | Ginger was significantly more effective than the placebo |
| Vutyavanich, 2001 | 250 mg ginger powder capsules (4 × daily) | Placebo | 4 | Ginger was significantly more effective than the placebo |
| Keating, 2002 | 250 mg ginger syrup (4 × daily) | Placebo | 14 | Ginger was more effective than the placebo |
| Sripamote, 2003 | 500 mg ginger powder capsules (3 × daily) | 10 mg vitamin B6 capsules (3 × daily) | 3 | Ginger and vitamin B6 were both significantly more effective for treating NVP |
| Willets, 2003 | 125 mg ginger extract capsules (4 × daily) | Placebo | 4 | Ginger was more effective than placebo for reducing nausea. No differences in vomiting |
| Smith, 2004 | 350 mg ginger capsules (3 × daily) | 25 mg vitamin B6 capsules (3 × daily) | 21 | Ginger was equivalent to vitamin B6 for reducing nausea |
| Chittumma, 2007 | 325 mg ginger capsules × 2 (3 × daily) | 12.5 mg vitamin B6 capsules × 2 (3 × daily) | 4 | Ginger was significantly more effective than vitamin B6 |
| Pongrojpaw, 2007 | 500 mg ginger powder capsules (2 × daily) | 50 mg dimenhydrinate capsules (2 × daily) | 7 | Ginger was as effective as dimenhydrinate |
| Ensiyeh and Sakineh, 2009 | 500 mg ginger powder capsules (2 × daily) | 20 mg vitamin B6 capsules (2 × daily) | 4 | Ginger was significantly more effective that vitamin B6 |
| Ozgoli, 2009 | 250 mg ginger powder capsules (4 × daily) | Placebo | 4 | Ginger was significantly more effective than placebo |
| Basirat, 2009 | 500 mg ginger biscuits (5 × daily) | Placebo | 4 | Ginger was significantly more effective than placebo in relieving nausea, and effective at reducing vomiting |
| Mohammadbeigi, 2011 | 200 mg ginger essence capsules (3 × daily) | a. Placebo b. 10 mg Metoclopramide capsules (3 × daily) | 5 | Ginger was less effective than metoclopramide, but the difference was non-significant |
| Haji Seid Javadi, 2013 | 250 mg ginger capsules (4 × daily) | 40 mg vitamin B6 capsules (2 × daily) | 4 | Ginger was equivalent to vitamin B6 for reducing nausea |