Table 1.

Comparison of microarray hybridization and RNA-Seq.

	MICROARRAY	RNA-Seq
Technology details6
Input RNA amount	High	Low
Probes	Yes	No
Resolution	Relatively Low	High; Single base
Background noise	High	Low
Cost	High	Relatively Low
Application35
Discovered gene range	Limited; Only on array	Wide; Whole transcriptome
Different isoform	Limited	Yes
Allelic expression	Limited	Yes
Rare/New transcript	Limited	Yes
Noncoding RNA	Limited	Yes