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. 2016 Apr 1;10(4):e0004592. doi: 10.1371/journal.pntd.0004592

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© 2016 Saini et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 5 — Flowcytometry analysis demonstrates reduction in percentage of CD3⁺CD4⁺gated CD25⁺FOXP3⁺ cells (see Materials and Methods). Dot plots show percentage of CD25⁺FOXP3⁺ cells in representative patients with RR, ENL as compared to stable BT, LL patients respectively. Histogram shows MFI (mean florescent intensity) of nuclear FOXP3 and intracellular TGF-β in each of RR and ENL as compared to respective BT and LL (Figs a, b). Bar diagram shows MFI of nuclear FOXP3 and TGF-β (mean±SD) in RR, ENL as compared to BT, LL leprosy groups respectively (Figs b, c). Data were analyzed using two tailed Mann-Whitney, p< 0.05 was considered as statistically significant. (), Parenthesis shows number of subjects tested. Abbreviations as Fig 1.