. 2016 Apr 1;10(4):e0004592. doi: 10.1371/journal.pntd.0004592

Table 3. Mean pg/ml ± SD of cytokines in culture supernatants of 48 hr.

M.leprae stimulated PBMC from 10 each of stable tuberculoid (BT), reversal reaction (RR) stable lepromatous leprosy (LL) and erythema leprosum reaction (ENL) patients investigated for gene expression study.

Cytokine	BT	RR	LL	ENL
IL-17A	101.9±2.6	219.8±28.07^***	45.52±22.7	650±195.2^***
IL-21	314±19.1	346±30.4^*	267.4±11.5	232.5±48.5
IL-22	561±118	492.8±115.0	633.1±89.1^***	96.72±93.0
IL-23A	62.6±51.2	131.9±45.9^**	23.64±10.4	48.51±45.2^*
IL-1β	13.6±16.3	7.3±1.1	8.5±4.4	22.4±12.2^**
IL-6	50.5±27.9	122±21.6^***	21.8±10.9	439.1±203.0^**
TGF-β	104.4±45.7	80.5±13.0	312±98.1	297.5±65.8

Classification according to Ridley Jopling classification [2,29]. Legend as in Table 2

*p< 0.01

** p< 0.001

*** p< 0.0001 by two tailed Mann Whitney test. P<0.05 was considered significant.