Table 5. Expression of surface molecules, cytokines, signaling molecules, chemokines, receptors and transcription factors evaluated by qPCR where fold change between stable and reaction groups showed significant differences in RR and ENL.

	RR	ENL		RR	ENL		RR	ENL
Surface Molecules			Cytokines			Signaling Molecules, Transcriptional Factors
CD247	ns	ns	CSF2	0.001	0.02	CEBPB	ns	0.03
CD28	0.0001	0.03	CSF3	0.001	0.02	CLEC7A	0.0001	ns
CD34	0.0001	ns	IFN-γ	0.001	0.05	S1PR1	ns	ns
CD3D	ns	ns	IL10	0.001	ns	FOXP3	0.001	0.03
CD3E	ns	0.01	IL12B	0.0001	ns	GATA3	0.0002	0.04
CD3G	ns	0.02	IL13	0.001	ns	JAK1	0.02	0.03
CD4	0.01	ns	IL15	0.001	ns	JAK2	0.01	ns
CD40LG	0.001	0.006	IL17A	0.0001	0.002	MMP13	0.001	ns
CD8A	0.001	ns	IL17C	0.001	0.005	MMP3	0.0003	ns
ICAM1	ns	ns	IL17D	0.001	0.04	MMP9	ns	ns
ICOS	0.0001	0.04	IL17F	0.001	0.001	NFATC2	0.005	ns
ISG20	ns	ns	IL18	0.002	ns	NFKB1	ns	ns
Chemokines			IL1β	ns	ns	RORC	0.0001	0.02
CCL1	0.0001	ns	IL2	0.0001	ns	SOCS1	ns	ns
CCL2	ns	ns	IL21	0.0001	0.04	SOCS3	0.01	ns
CCL20	0.0001	ns	IL22	0.0001	0.04	STAT3	ns	ns
CCL22	0.001	0.005	IL23A	0.0001	0.04	STAT4	0.01	ns
CCL7	ns	ns	IL25	0.0001	ns	STAT5A	ns	ns
CX3CL1	0.001	ns	IL27	0.0001	ns	STAT6	ns	ns
CXCL1	ns	ns	IL3	0.0001	ns	SYK	ns	ns
CXCL12	0.001	ns	IL4	0.0001	ns	TBX21	0.0001	ns
CXCL2	0.001	ns	IL5	0.0001	0.04	TIRAP	0.0001	ns
CXCL5	ns	ns	IL6	0.0001	0.02	TLR4	ns	ns
CXCL6	0.001	ns	TGFβ1	ns	ns	CACYBP	0.04	ns
IL8	ns	ns	TNF	ns	ns
Cytokine Receptors
IL12RB1	0.0008	0.04	IL7R	ns	ns	IL17RD	0.0001	ns
IL12RB2	0.001	ns	IL17RB	0.001	ns	IL17RE	0.0002	0.03
IL23R	0.0002	ns	IL17RC	0.0001	ns	IL6R	0.01	ns

p value calculated by Student’s t test. ns = non significant, Abbreviations as in legend to Table 1.