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. 2016 Apr 1;11(4):e0152772. doi: 10.1371/journal.pone.0152772

Table 2. Effects of TLS on the levels of MDA and the activities of SOD and T-AOC in the hippocampus and cerebral cortex.

Group Hippocampus Cerebral cortex
MDA (nmol/mg protein) SOD (U/mg protein) T-AOC (U/μg protein) MDA (nmol/mg protein) SOD (U/mg protein) T-AOC (U/μg protein)
Control 16.63 ± 2.12 ## 19.26 ± 0.62 ## 6.06 ± 1.23 # 18.13 ± 2.52 ## 24.03 ± 1.10 ## 51.36 ± 5.76 ##
Sham 11.47 ± 2.27 26.36 ± 1.17 7.95 ± 0.93 11.41 ± 1.15 34.18 ± 1.28 67.38 ± 3.73
Donepezil 13.52 ± 3.13 23.68 ± 1.29 7.80 ± 1.36 * 14.76 ± 2.01 35.90 ± 4.50 ** 66.54 ± 3.21 *
TLS 50 mg/kg 14.06 ± 3.07 26.13 ± 1.83 * 7.84 ± 0.55 * 15.11 ± 0.79 30.02 ± 1.79 64.32 ± 4.11 *
TLS 200 mg/kg 12.08 ± 2.67 * 28.07 ± 2.65 ** 8.41 ± 0.38 ** 12.83 ± 1.87 * 32.84 ± 2.36 ** 71.71 ± 1.72 **

Values indicated mean ± S.E.M. and were analyzed by one-way analysis of variance (ANOVA) followed by Tukey's multiple comparison test (n = 8).

#p < 0.05 and

##p < 0.01 compared with the sham group

*p < 0.05 and

**p < 0.01 compared with the control group.