Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Mar 24;11:1213–1223. doi: 10.2147/IJN.S93324

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 Markovic et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Averaged fluorescence diffusion curves over all spacers imaged (N=8), normalized to the intensity at x=0 per time point.

Notes: (A) Cy7.5 dye spacers, (B) 30 nm nanoparticle spacers, and (C) 200 nm nanoparticle spacers. (D) The average maximum spacer fluorescence intensity normalized to initial time point showing the continual decrease in maximum fluorescence over time. (E) The fluorescence area imaged (full width at half maximum) around the spacer as a function of time, averaged over all trials. As indicated, diffusion occurred continuously over time, with the maximum diffusion area observed on day 4 for 30 nm NPs, day 6 for 200 nm NPs, and continuously increasing area observed for free dye.

Abbreviations: Cy7.5, Cyanine 7.5; NPs, nanoparticles.